Which group contains insecticides that act as cholinesterase inhibitors?

Cholinesterase inhibitors are a class of insecticides that impede the enzyme cholinesterase, which is essential for the proper functioning of the nervous system in both insects and humans. Organophosphates are well-known for their mechanism of action as cholinesterase inhibitors. When organophosphates are applied, they bind to the active site of the cholinesterase enzyme, preventing it from breaking down acetylcholine. This leads to an accumulation of acetylcholine in the synaptic cleft, resulting in continuous stimulation of the nervous system, which is lethal to insects.

This mechanism is significant in pest control, as it allows for effective management of various insect populations, including mosquitoes. Understanding the role of cholinesterase inhibitors is vital for applicators regarding safety and efficacy when using these agents.

In contrast, the other groups do not primarily function as cholinesterase inhibitors. Pyrethroids operate by disrupting sodium channel function in nerves, neonicotinoids target nicotinic acetylcholine receptors, and insect growth regulators modify hormonal processes in insects rather than affecting cholinesterase. This highlights the unique role that organophosphates play in pest management through their action as cholinesterase inhibitors.